hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The Menopause Society acknowledges a lack of long-term data on how breast cancer survivors respond to hormone replacement therapy. Laura Trujillo, USA Today, 30 June 2026 Later analyses found the participants in the study were older than most women starting hormone replacement therapy and the risks of taking it were overstated. Angelica Peebles, CNBC, 26 June 2026 The review found that liraglutide was better for health outcomes than hormone replacement therapy. Angelica Stabile, FOXNews.com, 20 June 2026 The longer-term roadmap includes perimenopause monitoring, hormone replacement therapy calibration, and diagnostics for conditions like PCOS and endometriosis. Lily Mae Lazarus, Fortune, 17 June 2026 See All Example Sentences for hormone replacement therapy

Word History

First Known Use

1945, in the meaning defined above

Time Traveler
The first known use of hormone replacement therapy was in 1945

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Cite this Entry

“Hormone replacement therapy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hormone%20replacement%20therapy. Accessed 6 Jul. 2026.

Medical Definition

hormone replacement therapy

noun
: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
abbreviation HRT

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